Response of the pearl oyster Pinctada margaritifera to cadmium and chromium: Identification of molecular biomarkers

Archive ouverte

Gueguen, Yannick | Saulnier, Denis | Santini, Adrien | Magré, Kevin | Garen, Pierre | Bernagout, Solène | Nohl, Marine | Bouisset, Patrick | Helme, Herehia | Planes, Serge | Le Moullac, Gilles

Edité par HAL CCSD

International audience. This study was designed to identify in the pearl oyster Pinctada margaritifera, used as a bio-accumulator, molecular biomarkers for the presence of heavy metals in the lagoon environment. Pearl oysters were exposed to 2 concentrations (1 and 10 μg L− 1) of cadmium (Cd) and chromium (Cr) compared to a control. Twelve target genes encoding proteins potentially involved in the response to heavy metal contamination with antioxidant, detoxification or apoptosis activities were selected. P. margaritifera accumulated Cd but not Cr, and mortality was related to the amount of Cd accumulated in tissues. In response to Cd-Cr contamination, metallothionein (MT) was significantly up-regulated by Cd-Cr at both concentrations, while 7 others (SOD, CAT, GPX, GSTO, GSTM, CASP, MDR) were down-regulated. Based on the development of these molecular tools, we propose that the pearl oyster, P. margaritifera, could be used as a sentinel species for heavy metal contamination in the lagoons of tropical ecosystems.

Consulter en ligne


Du même auteur

Characterization of molecular processes involved in the pearl formation in Pinctada margaritifera for the sustainable development of pearl farming industry in French Polynesia. | Gueguen, Yannick

Characterization of molecular processes invol...

Archive ouverte | Gueguen, Yannick | International Symposium on Pearl Research | 2011-10-04

11 pages. International audience

Bacterial community characterization of water and intestine of the shrimp Litopenaeus stylirostris in a biofloc system | Cardona, Emilie

Bacterial community characterization of water...

Archive ouverte | Cardona, Emilie | ISSN: 1471-2180 | 2016-07-19

International audience. Background: Biofloc technology (BFT), a rearing method with little or no water exchange, is gaining popularity in aquaculture. In the water column, such systems develop conglomerates of microbes, algae and ...

Pinctada margaritifera responses to temperature and pH: Acclimation capabilities and physiological limits | Le Moullac, Gilles

Pinctada margaritifera responses to temperatu...

Archive ouverte | Le Moullac, Gilles | ISSN: 0272-7714 | 2016

International audience. The pearl culture is one of the most lucrative aquacultures worldwide. In many South Pacific areas, it depends on the exploitation of the pearl oyster Pinctada margaritifera and relies entirely on the envir...

Chargement des enrichissements...